Research

Our vast diversity of patients and passionate faculty foster an environment that has led to numerous scholarly works by our residents. Academic pursuits are encouraged through special stipends for publication and presentation as well as availability of a research elective. Our residents have an admirable track record of disseminating scientific observations. 

(residents = red; faculty = blue; neuropsychology fellow = green; *=  CMSRU medical student).

Manuscript Publications and Book Chapters

  • Rincon F, Morino T, Behrens D, Akbar U, Schorr C, Lee E, Gerber D, Parrillo J, Mirsen T. Association between out-of-hospital emergency department transfer and poor hospital outcome in critically ill stroke patients. J Crit Care 2011;26:620-5.
  • Hassan AE, Chaudhry SA, Zacharatos H, Khatri R, Akbar U, Suri MF, Qureshi AI. Increased rate of aspiration pneumonia and poor discharge outcome among acute ischemic stroke patients following intubation for endovascular treatment. Neurocrit Care 2012;16:246-50.
  • Akbar U, Rincon F, Carran M, Campellone JV, Milcarek B, Burakgazi E. Increased prevalence of temporary cardiac pacing in people with epilepsy. Seizure 2012;20:518-21.
  • Then R, Dominguez F. Paroxysmal Sneezing Heralding Posterior Circulation lschemia. Journal of American Geriatric Society (JAGS). 2012
  • Dham BS, Campellone JV. Post-partum paraparesis from spinal neurofibroma. Spine J 2012;12(7):e5-8.
  • Burakgazi E, Akbar U, Kelly J. Subclinical rhythmic electrographic discharges of adults in a patient with migraine. Clin EEG Neurosci 2012;43:165-8
  • Assadi M, Zerafati GM, Dham B, Contreras L, Akbar U, Zayas L, Leone P. The prevalence, burden and cognizance of migraine among adolescent girls. J Ped Neurol 2012;10:29-34
  • Kavi T, Moghal U, Popescu A. Multiple sclerosis ‘phenotype switch’ to Balo’s concentric sclerosis: Resistance to steroids, typical MRI findings and treatment with Plasmapheresis. J Neuroimaging 2013; 23(2): 270-271
  • Kavi T. Neurocysticercosis affecting multiple spinal segments: diagnosed with MRI and treated with surgical and pharmacological measures. J Neuroimaging 2013; 23(2): 270
  • Burakgazi E, Dalkilic A, Moghal U, Shah U, Carran M. A case of atypical absence seizure after electroconvulsive treatment in a patient with treatment-resistant depression. Clin EEG and Neurosci. 2013;44(1):62-9
  • Pollard JR, Eidelman O, Mueller GP, Dalgard CL, Crino PB, Anderson CT, Brand EJ, Burakgazi E, Ivaturi SK, Pollard HB. The TARC/sICAM5 ratio in patient plasma is a candidate biomarker for drug resistant epilepsy. Front Neurol. 2013;3:181
  • Shah U, Morrison T. A review of the symptomatic management of malignant gliomas in adults. J Natl Compr Canc Netw 2013;11(4):424-9
  • Assadi M, Zerafati G, Velazquez-Rodriguez Y, Echevarria L, Leone P. Do genetic influences determine the phenotypic severity of migraine? J Ped Neurol 2013: 11, 1-7.
  • Dababneh H, Shikhman A, Moussavi M, Guerrero WR, Panezai S, Kirmani JF. Teaching NeuroImages: Comatose patient with bilateral thalamic infarct due to internal carotid artery occlusion. Neurology. 2013 Apr 23;80(17)
  • Burakgazi E, Moghal U, Hughes D, Carran M. Does ictal whistling help to lateralize. Seizure. 2013 Nov 28. pii: S1059-1311(13)00320-8.
  • Burakgazi E, Bashir S, Doss V, Pellock J. The safety and tolerability of different intravenous administrations of levetiracetam, bolus versus infusion, in intensive care unit patients. Clin EEG Neurosci. 2013 Dec 19.
  • Campellone JV. Hereditary sensory and motor neuropathy with proximal predominance. J Clin Neuromusc Dis. 2013;14(4):180-183
  • Schneider JS, Gollomp SM. Sendek S, Colcher A, Cambi F, Du W. A randomized, controlled, delayed start trial of GM1 ganglioside in treated Parkinson’s disease patients. J Neurol Sci. 2013 Jan 15;324(1-2):l40-8.
  • Chahine LM, Daley J, Hom S, Colcher A, Hurtig H, Cantor C, Dahodwala N. Questionaire-based diagnosis of REM sleep behavior disorder in Parkinson’s disease. Mov Disord. 2013;28:1146-9.
  • Chahine LM, Qiang J, Ashbridge E, Minger J, Yearout D. Hom S, Colcher A, Hurtig HI, et al. Clinical and biochemical differences in patients having Parkinson's disease with vs. without GBA mutations. JAMA Neurol. 2013;70:852-8.
  • Chahine LM, Daley J, Horn S, Duda JE, Colcher A, Hurtig H, Cantor C, Dahodwala N. Association between dopaminergic medications and nocturnal sleep in early stage Parkinson’s disease. Parkinsonism Relat Disord. 2013
  • Kieburtz, K, McGarry A, McDermott M, Marder K, Kayson E, Walker, F, and the Huntington’s Study Group Investigators. A randomized, double-blind, placebo controlled trial of pridopidine in Huntington’s Disease. Mov Disord 2013;28:1407-15
  • McGarry A, Biglan K. Imaging in Huntington’s disease and other choreas. Neuroimaging of Movement Disorders. New York; Springer Science and Business Media, 2013.
  • Cudkowicz M, McDermott M, Kieburtz K, McGarry A, de Blieck E, and the 2CARE Investigators and Coordinators of the Huntington Study Group. Recruitment and retention challenges in 2CARE, a long-term therapeutic clinical trial of coenzyme Q10 in Huntington's disease. Neurotherapeutics 2013; 10(1): 177-8.
  • McGarry A, Biglan K. Improvement of freezing of gait with amantadine in a patient with oculopharyngeal muscular dystrophy and parkinsonism. Parkinsonism Relat Disord. 2013 Jun;19:643-4.
  • Burakgazi E, Bashir S, Doss V, Pellock J. The safety and tolerability of different intravenous administrations of levetiracetam, bolus versus infusion, in intensive care unit patients. Clin EEG Neurosci. 2014 Apr;45(2):89-91.
  • Burakgazi E, Moghal U, Hughes D, Carran M. Does ictal whistling help to lateralise. Seizure. 2014 Apr;23(4):314-7.
  • Bodofsky E, Campellone JV, Cohen JS, Caten H*, Schindleheim A. Contraction induced H-reflexes in the diagnosis of cervical radiculopathy. J Clin Neurophys 2015;32:244-6.
  • Zeylikman Y, Shah V, Shah U, Mirsen TR, Campellone JV. False-positive serum botulism bioassay in Miller–Fisher Syndrome. J Clin Neuromusc Dis 2015;17:27-9.
  • McGarry A, Biglan A, Marshall F. Huntington Disease. In: Rosenberg RN, Pascual JM, editors. Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease (Fifth Edition). Elsevier 2015.
  • Burakgazi E, French JA. Treatment of epilepsy in adults. Epileptic Disord 2016;18:228-39.
  • Burakgazi E. Neurostimulation devices used in treatment of epilepsy. Curr Treat Options Neurol. 2017;19(2):7.
  • McGarry A, McDermott M, … Colcher A, et al. A randomized, double-blind, placebo-controlled trial of coenzyme Q10 in Huntington Disease. Neurology 2017; 88: 152-159.
  • Ngo, L. Absolute spike frequency as a predictor of surgical outcome in temporal lobe epilepsy. Seizure 2017;47:83-86. PMID 28342319
  • Suero-Abreu GA, Cheng JZ, Then RK. Multiple recurrent ischemic strokes in a cancer patient: is there a role for the initiation of anticoagulation therapy for secondary stroke prevention? BMJ Case Rep 2017 PMID 28578306
  • Roberts B, Kavi T, Trzeciak S. Cardiac Arrest. In: Parillo J, Dellinger P, editors. Critical Care Medicine: Principles of Diagnosis and Management in the adult, 5E. (In press)
  • Taneja R, Hunter K, Burakgazi-Dalkilic ECarran M. Effect of sleep patterns on levetiracetam induced mood changes. Epilepsy Behav 2017;75:237-240. PMID 28827040
  • Nagele EP, Ross A, Then RK, Kavi T.  Interhemispheric subdural and subarachnoid haemorrhage in a patient with amphetamine-induced vasculitis.  BMJ Case Rep 2017 Dec 7, 2017. PMID: 29222209
  • Noto J, Nahra R, Kavi T. Disseminated coccidiomycosis related cervical intramedullary lesion causing quadriplegia in an immunocompetent host. BMJ Case Reports Dec 13, 2017. PMID: 29237660
  • Unger M, Georges J, Shaikh H, Kavi T. Moyamoya tipping point: Fatal bilateral MCA territory infarction following cocaine abuse. BMJ Case Reports 2018 Jan 18, 2018. PMID: 29351941
  • Kavi T, Madan N, et al. Angioinvasive Aspergillus associated stroke in an immunocompetent host following cardiac surgery and ECMO. Neurologist 2017;22:92-94. PMID: 28471899

Poster and Platform Presentations

  • Dham B. Prevalence and risk factors associated with acute ischemic stroke among HIV positive individuals: Preliminary analysis from a large administrative database. European Stroke Conference, Barcelona, Spain. May 2010
  • Dham B. Epidemiology and cognizance of migraines in teenagers. 53rd Annual American Headache Society (AHS) Conference, June 2011
  • Akbar U, Rincon F. Asystole after right insular ischemic stroke: understanding the heart and brain connection. AAN annual meeting 2011
  • Akbar U. Does epilepsy increase the risk for pacemaker placement? AAN annual meeting 2011
  • Akbar U, Shah U, Zeylikman Y, Rincon F, Burakgazi E, Carran M. Determinants of refractory status epilepticus and effect on hospital outcome: a single-center experience. Neurocritical Care Annual Meeting, September 2011
  • Akbar U, Dham B, Carran M. Benign-histology meningioma with extracranial metastasis. ANA annual meeting, September 2011
  • Akbar U, Burakgazi E, Kelly JJ. Valproate-responsive subclinical rhythmic electrographic discharges (SREDA) in a migraineur. ANA annual meeting, September 2011
  • Shah U, Akbar U, Wang C. Periodic lateralizing epileptiform discharges (PLEDs) causing persistent magnetic resonance imaging (MRI) changes in ipsilateral thalamus. Poster presentation; ANA annual meeting, September 2011
  • Assadi M, Dham B, Zerafati G, Veloski J, Leone P. Motor asymmetry in SCAs. ANA annual meeting, September 2011
  • Velazquez-Rodriguez Y, Akbar U, Burakgazi-Dalkilic E. Fatal dysautonomia associated with acute bacterial meningitis. ANA annual meeting, September 2011
  • Dham B. Benign-histology meningioma with extracranial metastasis. Poster presentation; ANA annual meeting, September 2011
  • Dham B, Assadi M. Motor asymmetry in SCAs. Poster presentation; ANA annual meeting, September 2011
  • Burakgazi E, Zayas L, Shah U. APACHE II and SAPS II scales in predicting phenytoin levels in critically ill patients. American Epilepsy Society annual meeting, December 2011.
  • Shikhman A, Mohammad M, Dababneh H, Korya D, Kirmani J. Lipids: what is good for ischemic stroke is bad for intracerebral hemorrhage”. Society of Vascular and Interventional Neurology annual meeting, October 2012.
  • Dham B. The epidemiology of status epilepticus in the United States. Platform presentation, AAN annual meeting; April 2012. (Research selected among “top 5 %”)
  • Shah U, Carran M. Neurosarcoidosis with granulomatous necrosis. AAN annual meeting; April, 2012
  • Shah U, Burakgazi E, Mogul U. Electroconvulsive therapy induced atypical status epilepticus. Annual ANA meeting, Boston, MA, October, 2012.
  • Kavi T, Velazquez-Rodriguez Y, Mirsen T, Campellone J. Effects of physiologic derangements on outcome of acute ischemic stroke patients after intravenous thrombolysis. 10th Annual Neurocritical Care Society Meeting, October 2012.
  • Kavi T, Moussavi M, Kirmani J, et al. UCSF ICH grading system is a better prognostic tool for spontaneous intracerebral hemorrhage when assessed at 24 hours after the event. 5th Society of Vascular and Interventional Neurology annual meeting, October 2012.
  • Moghal U, Dham B, Shah U. A fulminant case of atypical posterior reversible encephalopathy syndrome & status epilepticus. ANA annual meeting, 2012.
  • Zeylikman Y, Akbar U, Shah U, Burakgazi E, Carran M. Determinants of refractory status epilepticus on hospital outcome. Neurocritical care annual meeting 2012
  • Akbar U. Disparities in outcome of patients transferred from referring hospital emergency department with intracerebral hemorrhage versus another medical-surgical illness: a case-control study. AAN annual meeting, April 2013
  • Kavi T, Moghal U, Popescu A. Multiple sclerosis ‘phenotype switch’ to Balo’s oncentric sclerosis: resistance to steroids, typical MRI findings and treatment with lasmapheresis. 36th Annual Meeting of the American Society of Neuroimaging, January 2013.
  • Kavi T. Neurocysticercosis affecting multiple spinal segments: diagnosed with MRI and treated with surgical and pharmacological measures. American Society of Neuroimaging annual meeting, January 2013.
  • Shah R, Kavi T, Wang C. Timing of EEG in correlation to prognosis in post-cardiac arrest patients treated with therapeutic hypothermia. Platform Presentation, AAN annual meeting, March 2013
  • Alam S, Then R. Successful thrombolysis and thrombectomy in a patient with extensive cerebral venous thrombosis. AAN annual meeting, March 2013
  • Zeylikman Y, Shah V, Shah U, Burakgazi E, Campellone J, Mirsen T. serum false positive botulism assay in a case of Miller-Fisher syndrome. AAN 2013 annual meeting.
  • Kavi T, Moghal U, Popescu A. A case of Balo’s concentric sclerosis. American Society of Neuroimaging. Abstract accepted for annual conference. Las Vegas, NV (2013)
  • Shah R, Shah U, Bosley TM. Rhombencephalitis due to Listeria Monocytogens in immunocompetent patient. Poster presentation at ANA October 2013
  • Velazquez-Rodriguez Y, Kaur D, Campellone JV. A case of severe demyelinating polyneuropathy. 36th Annual Carrell-Krusen Neuromuscular Symposium. Dallas, TX, Feb 2014.
  • Fischer BD, Buono RJ, Cagande CC, Carran M. Case-based active learning as a method of introducing the neurosciences within a medical school curriculum. Annual meeting of the Society for Neuroscience: Washington, DC, 2014.
  • Bodofsky E, Cohen JS, Schindleheim A, Campellone JV, Caten H. Contraction induced H-reflexes in the diagnosis of cervical radiculopathy. AANEM Annual Meeting, October 2014.
  • Klinov V, Campellone JV. Comparison of length of hospital stay between treatment with plasma exchange versus IVIg in mild Guillain-Barré syndrome. AAN Annual meeting, April 2015
  • Then R, Patel M. Rare case of central nervous system invasion of mantle cell lymphoma with serial negative magnetic resonances: Case report and literature review. AAN annual meeting, April 2015.
  • Ko M, Cheng J, Then R. Early recurrence of ischemic strokes in a patient with active cholangiocarcinoma. American Heart Association meeting, April 2015.
  • Taneja R, Campellone JV, Carran M, Then R. Sustained hippus during electrographic status epilepticus and periodic lateralizing epileptiform discharges. Camden Scholar’s forum, Cooper Research Institute, April 2015
  • Baek R, Hong D, Macone B, Rader M, Casher A. Role of Green’s dementia profile and embedded performance validity tests in differentiating suboptimal effort from genuine neurocognitive impairment. American Academy of Clinical Neuropsychology (AACN) 13th Annual Conference, June 2015.
  • Hong D, Baek R, Macone B, Rader M, Casher A. Role of memory complaints inventory in distinguishing suboptimal neuropsychological performance from true cognitive impairment. American Academy of Clinical Neuropsychology (AACN) 13th Annual Conference, June 2015.
  • Taneja R, Syrow L. Acute inflammatory demyelinating polyneuropathy with voltage gated calcium channel antibodies”. AANEM annual meeting October 2015. (Winner of AANEM Foundation for Research and Education Junior Member Recognition Award).
  • Burakgazi-Dalkilic E, Strauman M, Kavi T, et al. Soluble ICAM5 concentrations unaltered by status epilepticus in patients with anoxic brain injury. 69th Annual American Epilepsy Society Meeting, December 2015.
  • Baek R, Hong D, Graziano J, Macone B, Fatzinger A, Rader M, Casher A. Diagnostic group differences in embedded performance validity testing among patients who scored below word memory test or medical symptom validity test failure cutoff. International Neuropsychological Society 44nd Annual Meeting, 2016
  • Cheng J, Suerro G, Then R. Multiple recurrent ischemic stroke in a patient with cholangiocarcinoma and initiation of anticoagulation therapy for secondary stroke prevention. AAN annual meeting; April 2016
  • Narula R, Masangkay N, Weston M, Patel A. Carcinomatous meningitis in linitus plastic. AAN annual meeting; April 2016
  • Hong D, Baek R, Graziano J, Macone B, Fatzinger A, Rader M, Casher A. Sensitivity and specificity of the dementia profile of word memory test and medical symptom validity test among patients who failed the easy subtests. International Neuropsychological Society 44nd Annual Meeting, 2016
  • Kieburtz K, Landwehrmeyer G, Reilmann R, Savola J, Eyal E, Grachev I, Borowsky B, McGarry A, Papapetropoulos S, Hayden M. Efficacy, safety, and tolerability of pridopidine in Huntington's disease: Results from the Phase II, double-blind, placebo-controlled, dose-ranging study, Pride-HD. AAN annual meeting; April 2017
  • McGarry A, Abler V, Auinger P, et al. Effect of pridopidine on total functional capacity (TFC) in Huntington's disease (HD): A comparison of Open-HART subjects with historical placebo controls. AAN annual meeting; April 2017
  • Veloso E, Ganesh J, Lacomis D, Campellone JV. Late-onset Pompe disease due to known and novel variants in GAA gene with possible contribution of a dystrophinopathy carrier state in a female patient. AAN annual meeting; April 2017
  • Gallagher M, Colcher A, McGarry A. Fentanyl induced chorea: A case report. 21st International Congress of Parkinson’s Disease and Movement Disorders; June 2017.
  • Kakadia B, Daci R, Suero-Abreu G, Then R. Would you use new oral anticoagulants (NOACs) for thromboprophylaxis in patients with an underlying hypercoagulable state? A literature review through a case report. AAN annual meeting; April 2018
  • McClane J, Gaughan J, Bowen F, Campellone JV. Current perspectives of neurologists regarding approach to thymectomy in non-thymomatous myasthenia gravis. Accepted for presentation at the 2018 annual meeting of the AANEM, October 2018.

Published Abstracts

  • Velazquez-Rodriguez Y, Akbar U, Burakgazi-Dalkilic E. Acute bacterial meningitis as a possible cause of severe dysautonomia leading to death. Ann Neurol 2011;70:S15. (Abstract M1205)
  • Akbar U, Burakgazi E, Kelly JJ. Valproate-responsive subclinical rhythmic electrographic discharges (SREDA) in a migraineur. Ann Neurol 2011;70:S15. (Abstract T1620)
  • Akbar U, Dham B, Carran M. Benign-histology meningioma with extracranial metastasis. Ann Neurol 2011;70:S15. (Abstract T1809)
  • Assadi M, Dham B, Zerafati G, Veloski J, Leone P. Motor asymmetry in SCAs. Ann Neurol 2011;70:S15. (Abstract T1809)
  • Shah U, Akbar U, Wang C. Persistent periodic lateralizing epileptiform discharges (PLEDs) causing persistent magnetic imaging (MRI) changes in ipsilateral thalamus. Ann Neurol 2011;70:S15. (Abstract S223)
  • Velazquez-Rodriguez Y, Akbar U, Campellone J, Mirsen T. Physiologic markers and echocardiogram as outcome predictors in patients with acute ischemic stroke after receiving thrombolysis. Neurocritical Care (2012) 17:S1–S337
  • Burakgazi E, Akbar U, Kelly J.  Subclinical rhythmic electrical discharges (SREDA) in a migraineur. Clin Electrocenceph Neurosci 2012;43:165-8. Epub 2012 Apr 16
  • Carran M, Velazquez-Rodriguez Y. High lipoprotein (a) in postpartum epilepsy. Epilepsy Currents 2012;(12 Supp)
  • Assadi M, G Zerafati, Velazquez-Rodriguez Y, L Echevarria, P Leone. Do genetic influences determine the phenotypic severity of migraine? Neurology 2013; 80:P06.155
  • Assadi M, G Zerafati, Velazquez-Rodriguez Y, P Leone. Phenotypic differences between probable migraine and definite migraine. Neurology 2013; 80:P03.107
  • Velazquez-Rodriguez Y, Assadi M, P Leone. Elevated cerebral lactate levels on multi-voxel magnetic resonance spectroscopy in metachromatic leukodystrophy. Neurology 2013;80:P03.016
  • Zeylikman YCampellone JV, Mirsen TR. Serum false positive botulism in a case with Miller Fisher syndrome. Neurology 2013;80:7 Supp P01.120
  • Klinov V, Campellone JV. Comparison of length of hospital stay between treatment with plasma exchange versus IVIg in mild Guillain-Barré syndrome. Neurology 2015;84:14 Supp P7.064
  • Then R, Patel M. Rare case of central nervous system invasion of mantle cell lymphoma with serial negative magnetic resonances: Case report and literature review. Neurology  2015;84:14 Supp P3.146
  • Cheng JZThen R. A case of multiple recurrent ischemic stroke in a patient with cholangiocarcinoma and initiation of anticoagulation therapy for secondary stroke prevention. Neurology 2016;86:16 Supp P4.342​
  • Veloso E, Ganesh J, Lacomis D, Campellone JV. Late-onset Pompe disease due to known and novel variants in GAA gene with possible contribution of a dystrophinopathy carrier state in a female patient. Neurology 2017, 88:16 Supp P2.121; 1526-632

Ongoing Research Activities

  • Platelet Oriented Inhibition in New TIA Trial (POINT)
  • Clobazam use in Epilepsia Partialis Continua - Pilot Study. A phase III, randomized, open label, single center, study on the effects of treatment of Epilepsia Partialis Continua with clobazam compared to treatment with or in addition to lorazepam and/or clonazepam.
  • Enroll-HD:A Prospective Registry Study in a Global Huntington’s Disease Cohort Unplanned Hospital Readmissions in Neurology Patients – (Neuro Readmit -1)
  • Long term, prospective, multinational, parallel-cohort study monitoring safety in patients with MS newly started on fingolimod once daily or treated with another approved disease-modifying therapy (PASSAGE)
  • Neuroimaging based calculation of Optic Nerve Sheath Diameter for non-invasive ICP measurement.
  • Impact of timing of Anti-seizure Medications in Status Epilepticus.
  • Exploratory Study of the Effects of Mindfulness Training on Behavior, Cognition, and Movement in Huntington's Disease
  • Imaging Dementia - Evidence for Amyloid Scanning (IDEAS) Study: A coverage with Evidence Development Longitudinal Cohort Study
  • An Open-Label Tolerability and Exploratory Efficacy Study of Zonisamide for Dyskinesias in Parkinson's Disease
  • A Randomized, Double-Blind, Placebo Controlled Study of Droxidopa for Fatigue in Parkinson's Disease (PD)
  • An Open-Label, Long Term Safety Study of SD-809 ER in Patients with Chorea Associated with Huntington's Disease. Alternatives for Reducing  Chorea in Huntingtons Disease (ARC HD)
  • Registry of Amyloid Positive Patients for Alzheimer's Disease Drug Research Trials (RAmP)